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ApoE4 Info

Here you will find all you need to know about the Apo ε4 allele.


Our Wiki attempts to bring you the most up-to-date research on different aspects of ApoE4.


An active discussion forum amongst ApoE4 carriers, discussing the latest research and prevention strategies.

About Us

We're a group of ordinary men and women, from all over the world, who've banded together in an effort to collect information... to save our very lives and the lives of those we care about. After participating in 23andMe, a personal genomics service, we learned that we carry the APOE-ε4 allele, putting us at high risk for Alzheimer's – a deadly, incurable, neurodegenerative disease – as well as other forms of dementia, and even heart disease and other maladies.

As if that wasn't frightening enough, imagine our chagrin upon learning that the medical community has arrived at NO consensus on prevention strategies for people with our genetic predisposition. The current advice from experts for ε4-carriers is wildly contradictory. We soon learned that we are genetic pioneers, modern-day canaries in the coal mine, searching for and testing out answers. 23andMe provided forums for us to talk with one another, and thus began page after page of contributions from all corners of the globe. We avidly began sharing and examining research, speaking to experts, comparing advice and strategies, challenging long-held notions, conducting n=1 experiments, tracking and sharing biomarkers, and more – all in an effort to find a prevention strategy for ε4-carriers. After spending over a year amassing hundreds of pages of information, we realized we were sitting upon a treasure trove that had never been collected in one place. In an effort to catalogue and organize our work, was born.

Alzheimer's News

Send an email to admin[AT]apoe4[DOT]info