Site Pages

ApoE4 Info

Here you will find all you need to know about the Apo ε4 allele.


Our Wiki attempts to bring you the most up-to-date research on different aspects of ApoE4.


An active discussion forum amongst ApoE4 carriers, discussing the latest research and prevention strategies.


List of Blogs related to ApoE4 or other members.

We're a group of ordinary men and women, from all over the world, who've banded together in an effort to collect information... to save our very lives and the lives of those we care about. After participating in 23andMe, a personal genomic service, we learned that we unknowingly carried the APOE-ε4 allele, putting us at high risk for Alzheimer's- a deadly, incurable, neurodegenerative disease- for which there is no cure. As if that wasn't frightening enough, imagine our chagrin upon learning that the medical community has NO consensus on prevention strategies for our population. The current advice from experts for ε4 carriers is wildly contradictory.We soon learned that we are epigenetic pioneers, modern day canaries in the coal mine, searching for answers. 23andMe provided forums for us to talk with one another; thus began page after page of contributions from all corners of the globe. We doggedly began sharing and examining research, speaking to experts, comparing advice and strategies, challenging long held notions, conducting n=1 experiments, tracking and sharing bio-markers, and more- all in an effort to find a prevention strategy for ε4 carriers. After spending over a year, amassing hundreds of pages of information, we realized we were sitting upon a treasure trove of information that had never been collected in one place. In an effort to catalogue and organize our work, was born.

Alzheimer's News

Send an email to