Search found 1925 matches

by NF52
Wed Feb 07, 2024 6:18 am
Forum: Prevention and Treatment
Topic: APOE 4/4 - Wisdom on telling siblings/children
Replies: 7
Views: 1066

Re: APOE 4/4 - Wisdom on telling siblings/children

I'm looking for thoughts and wisdom on a subject I think about often but with no solid answers. I'm in an APOE 4/4 in a large family with no family history of dementia*. I have five siblings in their 50s/60s and 2 kids in their 20's. None of them have had DNA tests as far as I can tell, but my kids...
by NF52
Tue Feb 06, 2024 2:17 pm
Forum: Announcements and Events
Topic: The Bredesen Protocol in South Africa
Replies: 9
Views: 2228

Re: The Bredesen Protocol in South Africa

Hi willem From pe By the grace of god maybe i came across your name in a dale breseden south africa search Im trying to convince my saiki team to follow his protocol I actually come from ct and went to school with tim noakes Hi tim How are your symtoms Mine dont sound as bad as yours were but they ...
by NF52
Sun Feb 04, 2024 8:58 am
Forum: Prevention and Treatment
Topic: APOE 4 testing other than 23 and me or DCL(Direct consumer labs)
Replies: 5
Views: 928

Re: APOE 4 testing other than 23 and me or DCL(Direct consumer labs)

Hi all APOE sisters and brothers, I have a quick question about APOE 4 testing? What platform are you using for APOE4 testing? I ask this especially after the 23 and me breach in security and for clients that do not want to use direct consumer labs because of insurance and long-term-health concerns...
by NF52
Sun Feb 04, 2024 8:28 am
Forum: Our Stories
Topic: New, almost 50, with 1 copy Apoe4 and a family history.
Replies: 8
Views: 693

Re: New, almost 50, with 1 copy Apoe4 and a family history.

Hi there! I'm a 49 year old woman (will be 50 in May), and to be honest I'm kind of freaking out. I'm not sure if it's turning 50, or being in perimenopause, or what. But lately my anxiety and fear over alzheimer's has been through the roof. First, a brief family history. My maternal grandmother ha...
by NF52
Fri Feb 02, 2024 8:02 am
Forum: Prevention and Treatment
Topic: CSF Test and AD Biomarkers
Replies: 3
Views: 419

Re: CSF Test and AD Biomarkers

Thanks for your reply, Nancy. To add a little more info on my test, from what I could read, the Abeta 42/40 ratio is used to try to predict the formation of Amyloid plaque because (in my simple understanding) Abeta 42 goes into the plaque formation and Abeta 40 does not. If the ratio of the two in ...
by NF52
Thu Feb 01, 2024 6:45 pm
Forum: Prevention and Treatment
Topic: CSF Test and AD Biomarkers
Replies: 3
Views: 419

Re: CSF Test and AD Biomarkers

Hi All, As a non-symptomatic APOE 4/4, I agreed to participate as a part of the Control Group in an ADRC study. This involves an extensive MRI session, providing a sample of CSF through LP (not fun), and annual cognitive testing. This seems worth it because it helps set a "wide perimeter fence...
by NF52
Sun Jan 28, 2024 10:23 am
Forum: Prevention and Treatment
Topic: p tau217
Replies: 5
Views: 735

Re: p tau217

Has anyone found a way to get a p-tau217 test? Getting a doctor to sign up here -- https://alzpath.bio/ -- might work, but it's not clear that AlzPath has made the test available yet. https://jamanetwork.com/journals/jamaneurology/fullarticle/2813751 Hi Brian, Thanks for sharing the full article on...
by NF52
Wed Jan 24, 2024 11:42 am
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 1808
Views: 345697

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

These forums are dedicated to ApoE4, but I have never observed your posts as taking on an ApoE4 viewpoint. ....you could express some greater empathy and kindness to the ApoE4 community. ... The three main themes we seem to face are lack of longevity, cardiovascular disease, and dementia. No one in...
by NF52
Sun Jan 21, 2024 8:54 am
Forum: Our Stories
Topic: Pregnant , age 44 & 4/4
Replies: 2
Views: 535

Re: Pregnant , age 44 & 4/4

Hi there - so we have a surprise pregnancy (but very much wanted). I am 43 but 44 in 2 weeks. I found out about my 4/4 status approx 4 years ago. I fast most days and take the recommended supplements etc. But i have been lax with my diet. My questions are , will this pregnancy ‘accelerate’ any issu...
by NF52
Sun Jan 21, 2024 8:35 am
Forum: Announcements and Events
Topic: PET scans, international locations
Replies: 1
Views: 402

Re: PET scans, international locations

I'm considering seeking a PET scan outside of the country. I've done some googling and found only a few locations. Some quite unusual. Is anyone aware of a published list of safe, accurate locations (likely universities?) to get a PET scan with a benchmark of accuracy internationally? My hope is th...